The series "Kaderimin Oyunu" is about the story of a strong woman in her 30s named Asiye. Asiye, who had a difficult childhood because of her stepmother, found happiness in Cemal, whom she married at the age of 17. However, over time, the birth of her children Nergis and Umut and the difficult living conditions cast a shadow over Asiye's happiness. For a better life, Cemal leaves her and her 2 children behind and establishes another home with a wealthy woman named Helin. Asiye, who is struggling to survive alone, meets Mahir, which changes her fate.